2. Gene
  3. ST18 - ST18 C2H2C-type zinc finger transcription factor Gene

ST18 - ST18 C2H2C-type zinc finger transcription factor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NZF3; NZF-3; ZNF387; ZC2H2C3; ZC2HC10

Gene ID: 9705 | Gene type: protein coding

About ST18

Cytogenetic location: 8q11.23 Genomic coordinates (GRCh38): 8:52,110,838-52,409,879 (from NCBI)

This gene has 27 transcripts (splice variants), 215 orthologues and 5 paralogues. Biased expression in brain (RPKM 3.7), stomach (RPKM 0.7) and 3 other tissues.

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of nitrogen compound metabolic process. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Apr 2022]

ST18 Products(60)

mRNA Protein Name
NM_001352826.2 NP_001339755.1 suppression of tumorigenicity 18 protein isoform a
NM_001352827.2 NP_001339756.1 suppression of tumorigenicity 18 protein isoform a
NM_001352828.2 NP_001339757.1 suppression of tumorigenicity 18 protein isoform a
NM_001352829.2 NP_001339758.1 suppression of tumorigenicity 18 protein isoform a
NM_001352830.2 NP_001339759.1 suppression of tumorigenicity 18 protein isoform a
NM_001352831.2 NP_001339760.1 suppression of tumorigenicity 18 protein isoform a
NM_001352832.2 NP_001339761.1 suppression of tumorigenicity 18 protein isoform a
NM_001352833.2 NP_001339762.1 suppression of tumorigenicity 18 protein isoform a
NM_001352834.2 NP_001339763.1 suppression of tumorigenicity 18 protein isoform a
NM_001352835.2 NP_001339764.1 suppression of tumorigenicity 18 protein isoform a
NM_001352836.2 NP_001339765.1 suppression of tumorigenicity 18 protein isoform a
NM_001352837.2 NP_001339766.1 suppression of tumorigenicity 18 protein isoform a
NM_001352838.2 NP_001339767.1 suppression of tumorigenicity 18 protein isoform a
NM_001352839.2 NP_001339768.1 suppression of tumorigenicity 18 protein isoform a
NM_001352840.2 NP_001339769.1 suppression of tumorigenicity 18 protein isoform a
NM_001352841.2 NP_001339770.1 suppression of tumorigenicity 18 protein isoform a
NM_001352842.2 NP_001339771.1 suppression of tumorigenicity 18 protein isoform a
NM_001352843.2 NP_001339772.1 suppression of tumorigenicity 18 protein isoform a
NM_001352844.2 NP_001339773.1 suppression of tumorigenicity 18 protein isoform a
NM_001352845.2 NP_001339774.1 suppression of tumorigenicity 18 protein isoform a
NM_001352846.2 NP_001339775.1 suppression of tumorigenicity 18 protein isoform a
NM_001352847.2 NP_001339776.1 suppression of tumorigenicity 18 protein isoform a
NM_001352848.2 NP_001339777.1 suppression of tumorigenicity 18 protein isoform a
NM_001352849.2 NP_001339778.1 suppression of tumorigenicity 18 protein isoform a
NM_001352850.2 NP_001339779.1 suppression of tumorigenicity 18 protein isoform a
NM_001352851.2 NP_001339780.1 suppression of tumorigenicity 18 protein isoform a
NM_001352852.2 NP_001339781.1 suppression of tumorigenicity 18 protein isoform a
NM_001352853.2 NP_001339782.1 suppression of tumorigenicity 18 protein isoform a
NM_001352854.2 NP_001339783.1 suppression of tumorigenicity 18 protein isoform a
NM_001352855.2 NP_001339784.1 suppression of tumorigenicity 18 protein isoform a
NM_001352856.2 NP_001339785.1 suppression of tumorigenicity 18 protein isoform a
NM_001352857.2 NP_001339786.1 suppression of tumorigenicity 18 protein isoform a
NM_001352858.2 NP_001339787.1 suppression of tumorigenicity 18 protein isoform c
NM_001352859.2 NP_001339788.1 suppression of tumorigenicity 18 protein isoform c
NM_001352860.2 NP_001339789.1 suppression of tumorigenicity 18 protein isoform c
NM_001352861.2 NP_001339790.1 suppression of tumorigenicity 18 protein isoform b
NM_001352862.2 NP_001339791.1 suppression of tumorigenicity 18 protein isoform b
NM_001352863.2 NP_001339792.1 suppression of tumorigenicity 18 protein isoform b
NM_001352864.2 NP_001339793.1 suppression of tumorigenicity 18 protein isoform b
NM_001352865.2 NP_001339794.1 suppression of tumorigenicity 18 protein isoform b
NM_001352866.2 NP_001339795.1 suppression of tumorigenicity 18 protein isoform b
NM_001352867.2 NP_001339796.1 suppression of tumorigenicity 18 protein isoform b
NM_001352868.2 NP_001339797.1 suppression of tumorigenicity 18 protein isoform b
NM_001352869.2 NP_001339798.1 suppression of tumorigenicity 18 protein isoform b
NM_001352870.2 NP_001339799.1 suppression of tumorigenicity 18 protein isoform d
NM_001352871.2 NP_001339800.1 suppression of tumorigenicity 18 protein isoform d
NM_001352872.2 NP_001339801.1 suppression of tumorigenicity 18 protein isoform d
NM_001352873.2 NP_001339802.1 suppression of tumorigenicity 18 protein isoform d
NM_001352874.2 NP_001339803.1 suppression of tumorigenicity 18 protein isoform d
NM_001352875.2 NP_001339804.1 suppression of tumorigenicity 18 protein isoform d
NM_001352876.2 NP_001339805.1 suppression of tumorigenicity 18 protein isoform f
NM_001352877.2 NP_001339806.1 suppression of tumorigenicity 18 protein isoform e
NM_001352878.2 NP_001339807.1 suppression of tumorigenicity 18 protein isoform e
NM_001352879.1 NP_001339808.1 suppression of tumorigenicity 18 protein isoform g
NM_001352880.1 NP_001339809.1 suppression of tumorigenicity 18 protein isoform g
NM_001352881.1 NP_001339810.1 suppression of tumorigenicity 18 protein isoform g
NM_001352882.1 NP_001339811.1 suppression of tumorigenicity 18 protein isoform g
NM_001352883.2 NP_001339812.1 suppression of tumorigenicity 18 protein isoform h
NM_001352884.2 NP_001339813.1 suppression of tumorigenicity 18 protein isoform h
NM_014682.3 NP_055497.1 suppression of tumorigenicity 18 protein isoform a

ST18 Protein Structure

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (366 - 394)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (410 - 439)

MYT1

MYT1: Myelin transcription factor 1 (480 - 716)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (723 - 751)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (765 - 795)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (813 - 843)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (868 - 895)

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  • 1047 a.a.
Protein Preferred Names Protein Names

suppression of tumorigenicity 18 protein

ST18, C2H2C-type zinc finger

Related Diseases

Diseases Alias
Pemphigus
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13845 ST18 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ST18 RGD RGD:708566
Felis catus ST18 VGNC VGNC:65718
Canis familiaris ST18 VGNC VGNC:46849
Bos taurus ST18 VGNC VGNC:35330
Macaca mulatta ST18 VGNC VGNC:77959
Mus musculus ST18 MGD MGI:2446700
Others ST18 NCBI