2. Gene
  3. USP6NL - USP6 N-terminal like Gene

USP6NL - USP6 N-terminal like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RNTRE; TRE2NL; USP6NL-IT1

Gene ID: 9712 | Gene type: protein coding

About USP6NL

Cytogenetic location: 10p14 Genomic coordinates (GRCh38): 10:11,460,510-11,611,650 (from NCBI)

This gene has 6 transcripts (splice variants), 217 orthologues and 45 paralogues. Broad expression in testis (RPKM 11.0), esophagus (RPKM 10.8) and 24 other tissues.

Summary

Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including plasma membrane to endosome transport; positive regulation of GTPase activity; and retrograde transport, plasma membrane to Golgi. Located in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

USP6NL Products(5)

mRNA Protein Name
NM_001080491.5 NP_001073960.1 USP6 N-terminal-like protein isoform 2
NM_001391959.1 NP_001378888.1 USP6 N-terminal-like protein isoform 3
NM_001391960.1 NP_001378889.1 USP6 N-terminal-like protein isoform 4
NM_001391961.1 NP_001378890.1 USP6 N-terminal-like protein isoform 5
NM_014688.5 NP_055503.1 USP6 N-terminal-like protein isoform 1

USP6NL Protein Structure

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (104 - 312)

  • 0
  • 200
  • 400
  • 600
  • 828 a.a.
Protein Preferred Names Protein Names

USP6 N-terminal-like protein

related to the N-terminus of tre

Related Diseases

Diseases Alias
Nipah Virus Encephalitis

Equine Morbillivirus
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15567 USP6NL Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris USP6NL VGNC VGNC:48204
Macaca mulatta USP6NL VGNC VGNC:79055
Rattus norvegicus USP6NL RGD RGD:1311786
Bos taurus USP6NL VGNC VGNC:36737
Mus musculus USP6NL MGD MGI:2138893
Felis catus USP6NL VGNC VGNC:66897