Sgsm2 - small G protein signaling modulator 2 Gene

Also Known as Rutbc1; mKIAA0397; D630003G22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 97761

Summary

Enables GTPase activator activity. Predicted to be involved in activation of GTPase activity; intracellular protein transport; and late endosome to Golgi transport. Located in melanosome. Is expressed in brain and embryo. Orthologous to human SGSM2 (small G protein signaling modulator 2). [provided by Alliance of Genome Resources, Apr 2022]

Sgsm2 Products (2)

mRNA Protein Name
NM_001374688.1 NP_001361617.1 small G protein signaling modulator 2 isoform 2
NM_197943.3 NP_922934.2 small G protein signaling modulator 2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IMP
IMP: Inferred from mutant phenotype
26620560 MGI
Cellular Component GO Annotation Evidence References Source
located in melanosome IDA
IDA: Inferred from direct assay
26620560 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small G protein signaling modulator 2

  • RUN and TBC1 domain containing 1

  • RUN and TBC1 domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12814 SGSM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgsm2 NCBI NCBI:9905