2. Gene
  3. Tmem132a - transmembrane protein 132A Gene

Tmem132a - transmembrane protein 132A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Orai1; Hspa5bp1; 6720481D13Rik

Gene ID: 98170 | Gene type: protein coding

About Tmem132a

Summary

Predicted to be involved in negative regulation of programmed cell death. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; dorsal root ganglion; genitourinary system; and lung. Orthologous to human TMEM132A (transmembrane protein 132A). [provided by Alliance of Genome Resources, Apr 2022]

Tmem132a Products(2)

mRNA Protein Name
NM_001378918.1 NP_001365847.1 transmembrane protein 132A isoform 2 precursor
NM_133804.2 NP_598565.2 transmembrane protein 132A isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
33324648 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
33324648 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
33324648 MGI
acts upstream of or within positive regulation of Wnt protein secretion IMP
IMP: Inferred from mutant phenotype
33324648 MGI
acts upstream of or within positive regulation of Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
33324648 MGI
acts upstream of or within positive regulation of protein binding IMP
IMP: Inferred from mutant phenotype
33324648 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
33324648 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
33324648 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 132A

HSPA5-binding protein 1

heat shock 70kDa protein 5 binding protein 1

heat shock protein 5 binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14663 TMEM132A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem132a NCBI NCBI:54972