Gorab - golgin, RAB6-interacting Gene

Also Known as NTKL-BP1; Scyl1bp1; SCYL1-BP1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 98376

Summary

Acts upstream of or within hair follicle morphogenesis; non-motile cilium assembly; and positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Located in cytoplasm. Is expressed in brain. Human ortholog(s) of this gene implicated in geroderma osteodysplasticum. Orthologous to human GORAB (golgin, RAB6 interacting). [provided by Alliance of Genome Resources, Apr 2022]

Gorab Products (2)

mRNA Protein Name
NM_001313738.1 NP_001300667.1 RAB6-interacting golgin isoform 2
NM_178883.6 NP_849214.2 RAB6-interacting golgin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12783284 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within hair follicle morphogenesis IMP
IMP: Inferred from mutant phenotype
26967474 MGI
acts upstream of or within non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
26967474 MGI
acts upstream of or within positive regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
26967474 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12783284 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RAB6-interacting golgin

  • N-terminal kinase-like-binding protein 1

  • NTKL-binding protein 1

  • SCY1-like 1 binding protein 1

  • SCYL1-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05600 GORAB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gorab NCBI NCBI:92344