2. Gene
  3. TRIM66 - tripartite motif containing 66 Gene

TRIM66 - tripartite motif containing 66 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TIF1D; C11orf29; TIF1DELTA

Gene ID: 9866 | Gene type: protein coding

About TRIM66

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,612,040-8,683,231 (from NCBI)

This gene has 13 transcripts (splice variants), 185 orthologues and 80 paralogues. Broad expression in testis (RPKM 4.5), skin (RPKM 3.3) and 25 other tissues.

Summary

Predicted to enable chromatin binding activity and identical protein binding activity. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Located in aggresome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM66 Products(4)

mRNA Protein Name
NM_001388022.1 NP_001374951.1 tripartite motif-containing protein 66 isoform 2
NM_001388023.1 NP_001374952.1 tripartite motif-containing protein 66 isoform 3
NM_001388024.1 NP_001374953.1 tripartite motif-containing protein 66 isoform 4
NM_014818.2 NP_055633.1 tripartite motif-containing protein 66 isoform 1

TRIM66 Protein Structure

zf-B_box

zf-B_box: B-box zinc finger (64 - 99)

PHD

PHD: PHD-finger (972 - 1016)

Bromodomain

Bromodomain: Bromodomain (1050 - 1132)

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  • 1216 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 66

transcriptional intermediary factor 1 delta

Related Diseases

Diseases Alias
Brain Oligodendroglioma

Oligodendroglioma Of Brain
Non-Invasive Bladder Urothelial Carcinoma

Stage 0 Bladder Urothelial Carcinoma
Cystathioninuria

Cystathionase Deficiency

Gamma-Cystathionase Deficiency

Cystathione Gamma-Lyase Deficiency Syndrome

Cystathionine Gamma-Lyase Deficiency Syndrome

CSTNU
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15066 TRIM66 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TRIM66 VGNC VGNC:66549
Macaca mulatta TRIM66 VGNC VGNC:79766
Mus musculus TRIM66 MGD MGI:2152406
Bos taurus TRIM66 VGNC VGNC:36348
Rattus norvegicus TRIM66 RGD RGD:1595847
Canis familiaris TRIM66 VGNC VGNC:47833