TRIM66 - tripartite motif containing 66 Gene

Also Known as TIF1D; C11orf29; TIF1DELTA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9866

About TRIM66

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,612,040-8,683,231 (from NCBI)

This gene has 13 transcripts (splice variants), 185 orthologues and 80 paralogues. Broad expression in testis (RPKM 4.5), skin (RPKM 3.3) and 25 other tissues.

Summary

Predicted to enable chromatin binding activity and identical protein binding activity. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Located in aggresome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM66 Products (4)

mRNA Protein Name
NM_001388022.1 NP_001374951.1 tripartite motif-containing protein 66 isoform 2
NM_001388023.1 NP_001374952.1 tripartite motif-containing protein 66 isoform 3
NM_001388024.1 NP_001374953.1 tripartite motif-containing protein 66 isoform 4
NM_014818.2 NP_055633.1 tripartite motif-containing protein 66 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
25593309 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM66 Protein Structure

zf-B_box

zf-B_box: B-box zinc finger (64 - 99)

PHD

PHD: PHD-finger (972 - 1016)

Bromodomain

Bromodomain: Bromodomain (1050 - 1132)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1216 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 66

  • transcriptional intermediary factor 1 delta

Related Diseases

Diseases Alias
Brain Oligodendroglioma

  • Oligodendroglioma Of Brain
Non-Invasive Bladder Urothelial Carcinoma

  • Stage 0 Bladder Urothelial Carcinoma
Cystathioninuria

  • Cystathionase Deficiency

  • Gamma-Cystathionase Deficiency

  • Cystathione Gamma-Lyase Deficiency Syndrome

  • Cystathionine Gamma-Lyase Deficiency Syndrome

  • CSTNU
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15066 TRIM66 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TRIM66 VGNC VGNC:66549
Macaca mulatta TRIM66 VGNC VGNC:79766
Mus musculus TRIM66 MGD MGI:2152406
Bos taurus TRIM66 VGNC VGNC:36348
Rattus norvegicus TRIM66 RGD RGD:1595847
Canis familiaris TRIM66 VGNC VGNC:47833
Others TRIM66 NCBI