RBM19 - RNA binding motif protein 19 Gene

Also Known as Mrd1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9904

About RBM19

Cytogenetic location: 12q24.13-q24.21 Genomic coordinates (GRCh38): 12:113,816,740-113,966,325 (from NCBI)

This gene has 7 transcripts (splice variants), 191 orthologues and 36 paralogues. Ubiquitous expression in testis (RPKM 6.2), spleen (RPKM 5.9) and 25 other tissues.

Summary

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

RBM19 Products (3)

mRNA Protein Name
NM_001146698.2 NP_001140170.1 probable RNA-binding protein 19
NM_001146699.2 NP_001140171.1 probable RNA-binding protein 19
NM_016196.4 NP_057280.2 probable RNA-binding protein 19

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
16027046 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBM19 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (4 - 72)

(298 - 363)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (404 - 473)

(589 - 642)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (732 - 804)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (834 - 904)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 960 a.a.
Protein Preferred Names Protein Names

probable RNA-binding protein 19

Related Diseases

Diseases Alias
Ulnar-Mammary Syndrome

  • Schinzel Syndrome

  • UMS

  • Pallister Ulnar-Mammary Syndrome

  • Ulnar-Mammary Syndrome Of Pallister
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11738 RBM19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RBM19 VGNC VGNC:33790
Rattus norvegicus RBM19 RGD RGD:1308928
Canis familiaris RBM19 VGNC VGNC:45413
Macaca mulatta RBM19 VGNC VGNC:76559
Mus musculus RBM19 MGD MGI:1921361
Felis catus RBM19 VGNC VGNC:64523
Others RBM19 NCBI