SUPT7L - SPT7 like, STAGA complex subunit gamma Gene

Also Known as SPT7L; STAF65; SUPT7H; STAF65G; STAF65(gamma)

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9913

About SUPT7L

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,642,568-27,663,614 (from NCBI)

This gene has 5 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in brain (RPKM 10.8), spleen (RPKM 8.8) and 25 other tissues.

Summary

SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

SUPT7L Products (5)

mRNA Protein Name
NM_001282729.2 NP_001269658.1 STAGA complex 65 subunit gamma isoform a
NM_001282730.2 NP_001269659.1 STAGA complex 65 subunit gamma isoform b
NM_001282731.2 NP_001269660.1 STAGA complex 65 subunit gamma isoform b
NM_001282732.2 NP_001269661.1 STAGA complex 65 subunit gamma isoform c
NM_014860.3 NP_055675.1 STAGA complex 65 subunit gamma isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15870280 GOA
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
11564863 GOA
Biological Process GO Annotation Evidence References Source
involved in maintenance of protein location in nucleus IDA
IDA: Inferred from direct assay
15870280 GOA
Cellular Component GO Annotation Evidence References Source
part of SAGA complex IDA
IDA: Inferred from direct assay
11564863 GOA
located in nucleus IDA
IDA: Inferred from direct assay
15870280 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SUPT7L Protein Structure

Bromo_TP

Bromo_TP: Bromodomain associated (151 - 229)

  • 0
  • 100
  • 200
  • 300
  • 414 a.a.
Protein Preferred Names Protein Names

STAGA complex 65 subunit gamma

  • SPT7 like, STAGA complex gamma subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14040 SUPT7L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SUPT7L VGNC VGNC:65851
Mus musculus SUPT7L MGD MGI:1919445
Rattus norvegicus SUPT7L RGD RGD:1562206
Bos taurus SUPT7L VGNC VGNC:35482
Macaca mulatta SUPT7L VGNC VGNC:78247
Others SUPT7L NCBI