Arfgef2 - ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) Gene

Mus musculus

Also known as BIG2; E230011G24Rik

Gene ID: 99371 | Gene type: protein coding

About Arfgef2

Summary

Predicted to enable several functions, including GABA Receptor binding activity; guanyl-nucleotide exchange factor activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; positive regulation of tumor necrosis factor production; and receptor recycling. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and recycling endosome. Is expressed in brown fat; central nervous system; duodenum; thymus; and trunk. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Arfgef2 Products(1)

mRNA	Protein	Name
NM_001085495.2	NP_001078964.1	brefeldin A-inhibited guanine nucleotide-exchange protein 2

Protein Preferred Names

Protein Names

brefeldin A-inhibited guanine nucleotide-exchange protein 2

brefeldin A-inhibited GEP 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00903	ARFGEF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arfgef2	NCBI	NCBI:10564

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