Golga2 - golgi autoantigen, golgin subfamily a, 2 Gene
Also Known as GM130
Species: Mus musculus
Summary
Enables importin-alpha family protein binding activity. Involved in asymmetric cell division and meiotic spindle assembly. Acts upstream of or within Golgi localization and positive regulation of axonogenesis. Located in Golgi apparatus; perinuclear region of cytoplasm; and spindle pole. Is expressed in several structures, including eye; gonad; jaw bone; thoracic segment skeleton; and unsegmented mesenchyme. Orthologous to several human genes including GOLGA2 (golgin A2). [provided by Alliance of Genome Resources, Apr 2022]
Golga2 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080968.2 | NP_001074437.2 | golgin subfamily A member 2 isoform b |
| NM_001362695.2 | NP_001349624.2 | golgin subfamily A member 2 isoform c |
| NM_001362696.2 | NP_001349625.2 | golgin subfamily A member 2 isoform d |
| NM_001362697.2 | NP_001349626.2 | golgin subfamily A member 2 isoform e |
| NM_001362698.2 | NP_001349627.2 | golgin subfamily A member 2 isoform f |
| NM_133852.3 | NP_598613.3 | golgin subfamily A member 2 isoform a |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables importin-alpha family protein binding |
IDA
IDA: Inferred from direct assay
|
26165940 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21111240 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within Golgi localization |
IMP
IMP: Inferred from mutant phenotype
|
21111240 | MGI |
| involved in asymmetric cell division |
IMP
IMP: Inferred from mutant phenotype
|
21552007 | MGI |
| acts upstream of axonogenesis |
IMP
IMP: Inferred from mutant phenotype
|
21111240 | MGI |
| involved in meiotic spindle assembly |
IMP
IMP: Inferred from mutant phenotype
|
21552007 | MGI |
| acts upstream of or within positive regulation of axonogenesis |
IMP
IMP: Inferred from mutant phenotype
|
21111240 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in Golgi apparatus |
IDA
IDA: Inferred from direct assay
|
12646573 | MGI |
| located in Golgi membrane |
IDA
IDA: Inferred from direct assay
|
29437892 | MGI |
| located in cis-Golgi network |
IDA
IDA: Inferred from direct assay
|
11784862 | MGI |
| located in perinuclear region of cytoplasm |
IDA
IDA: Inferred from direct assay
|
17046993 | MGI |
| located in spindle pole |
IDA
IDA: Inferred from direct assay
|
21552007 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
golgin subfamily A member 2 |
|
|