Serpini1 - serpin family I member 1 Gene

Also Known as PI-12; raPIT5a

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 116459

Summary

Enables serine-type endopeptidase inhibitor activity. Involved in positive regulation of neuron projection development and regulation of cell adhesion. Predicted to be located in neuronal cell body and secretory granule lumen. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (Serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpini1 Products (1)

mRNA Protein Name
NM_053779.2 NP_446231.1 neuroserpin precursor
Molecular Function GO Annotation Evidence 参考文献 由来
enables serine-type endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
12438159 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
23825416 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuroserpin

  • peptidase inhibitor 12

  • protease inhibitor 17

  • serine (or cysteine) peptidase inhibitor, clade I, member 1

  • serine (or cysteine) proteinase inhibitor clade member 1

  • serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1

  • serine protea

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Serpini1 NCBI NCBI:5274