PPP1R35 - protein phosphatase 1 regulatory subunit 35 Gene

Also Known as C7orf47

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 221908

About PPP1R35

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,435,282-100,436,698 (from NCBI)

This gene has 5 transcripts (splice variants) and 98 orthologues. Broad expression in testis (RPKM 18.3), spleen (RPKM 14.1) and 25 other tissues.

Summary

Predicted to enable Phosphatase binding activity and protein Phosphatase inhibitor activity. Predicted to be involved in negative regulation of Phosphatase activity. [provided by Alliance of Genome Resources, Apr 2022]

PPP1R35 Products (2)

mRNA Protein Name
NM_001346938.2 NP_001333867.1 protein phosphatase 1 regulatory subunit 35 isoform 2
NM_145030.4 NP_659467.1 protein phosphatase 1 regulatory subunit 35 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
30168418 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of centriole elongation IMP
IMP: Inferred from mutant phenotype
30168418 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in centriole IDA
IDA: Inferred from direct assay
30168418 GOA
located in centrosome IDA
IDA: Inferred from direct assay
30168418 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPP1R35 Protein Structure

PPP1R35_C

PPP1R35_C: Protein phosphatase 1 regulatory subunit 35 C-terminus (104 - 249)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

protein phosphatase 1 regulatory subunit 35

  • UPF0683 protein C7orf47

関連疾患

Diseases Alias
Bardet-Biedl Syndrome 1

  • BBS1

  • Bardet-Biedl Syndrome 1, Modifier Of

  • Bardet-Biedl Syndrome

  • BBS

  • Bardet-Biedl Syndrome, Type 1

  • Laurence-Moon-Bardet-Biedl Syndrome
Primary Autosomal Recessive Microcephaly

  • Autosomal Recessive Primary Microcephaly

  • Mcph

  • True Microcephaly

  • Microcephalia Vera

  • Microcephaly Vera

  • Microcephaly Primary Hereditary

  • Microcephaly, Primary, Autosomal Recessive

  • Primary Microcephaly
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS10997 PPP1R35 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta PPP1R35 VGNC VGNC:76331
Canis familiaris PPP1R35 VGNC VGNC:44893
Mus musculus PPP1R35 MGD MGI:1922853
Felis catus PPP1R35 VGNC VGNC:107810
Rattus norvegicus PPP1R35 RGD RGD:1584367
Others PPP1R35 NCBI