GOLGA3 - golgin A3 Gene

Also Known as MEA-2; GCP170

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 2802

About GOLGA3

Cytogenetic location: 12q24.33 Genomic coordinates (GRCh38): 12:132,768,914-132,829,081 (from NCBI)

This gene has 41 transcripts (splice variants), 199 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 8.3), brain (RPKM 6.7) and 25 other tissues.

Summary

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during Mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Feb 2010]

GOLGA3 Products (9)

mRNA Protein Name
NM_001172557.2 NP_001166028.1 golgin subfamily A member 3 isoform 2
NM_001389683.1 NP_001376612.1 golgin subfamily A member 3 isoform 1
NM_001389684.1 NP_001376613.1 golgin subfamily A member 3 isoform 1
NM_001389685.1 NP_001376614.1 golgin subfamily A member 3 isoform 1
NM_001389686.1 NP_001376615.1 golgin subfamily A member 3 isoform 3
NM_001389687.1 NP_001376616.1 golgin subfamily A member 3 isoform 3
NM_001389688.1 NP_001376617.1 golgin subfamily A member 3 isoform 3
NM_001389689.1 NP_001376618.1 golgin subfamily A member 3 isoform 4
NM_005895.4 NP_005886.2 golgin subfamily A member 3 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
14522980 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in Golgi membrane IDA
IDA: Inferred from direct assay
14522980 GOA
located in cytosol IDA
IDA: Inferred from direct assay
14522980 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

golgin subfamily A member 3

  • Golgi membrane associated protein

関連疾患

Diseases Alias
Smallpox

  • Variola

  • Ordinary Smallpox

  • Alastrim

  • Amaas
Primary Ciliary Dyskinesia

  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary
Fanconi Anemia, Complementation Group C

  • Fanconi Anemia Complementation Group C

  • FANCC

  • Facc

  • Fac

  • Fa3

  • Fanconi Pancytopenia Type 3

  • Fanconi Pancytopenia, Type 3

  • Faces Syndrome

  • Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies

  • Friedman-Goodman Syndrome

  • Abnormality Of The Face
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05584 GOLGA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus GOLGA3 VGNC VGNC:29484
Canis familiaris GOLGA3 VGNC VGNC:41339
Felis catus GOLGA3 VGNC VGNC:62638
Mus musculus GOLGA3 MGD MGI:96958
Macaca mulatta GOLGA3 VGNC VGNC:73106
Rattus norvegicus GOLGA3 RGD RGD:1305262
Others GOLGA3 NCBI