Mtap - methylthioadenosine phosphorylase Gene

Also Known as Cc1-6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 298227

Summary

Enables S-methyl-5-thioadenosine Phosphorylase activity. Involved in response to testosterone. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine Phosphorylase). [provided by Alliance of Genome Resources, Apr 2022]

Mtap Products (1)

mRNA Protein Name
NM_001394049.1 NP_001380978.1 S-methyl-5'-thioadenosine phosphorylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables S-methyl-5-thioadenosine phosphorylase activity IDA
IDA: Inferred from direct assay
6401802 RGD
Biological Process GO Annotation Evidence References Source
involved in response to testosterone IEP
IEP: Inferred from expression pattern
6774734 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

S-methyl-5'-thioadenosine phosphorylase

  • 5'-methylthioadenosine phosphorylase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-156680 Vopimetostat Inhibitor 99.55% Phase 2
HY-16933 L-Alanosine Inhibitor 99.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (44)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153390 AMG-193 Inhibitor 99.71% Unkown
HY-148419 Ralometostat Inhibitor 99.90% Unkown
HY-101496 MT-DADMe-ImmA Inhibitor 99.17% Unkown
HY-112130 AGI-24512 Inhibitor 99.46% Unkown
HY-145778 AGI-41998 Inhibitor 98.72% Unkown
HY-162353 AZ'9567 99.19% Unkown
HY-145777 AGI-43192 Inhibitor 99.47% Unkown
HY-138684 MRTX9768 Inhibitor 99.60% Unkown
HY-153390A (R)-AMG-193 Inhibitor 98.53% Unkown
HY-162783 AZ-PRMT5i-1 Inhibitor / Unkown
HY-138684A MRTX9768 hydrochloride Inhibitor 99.88% Unkown
HY-158143 AZD3470 99.74% Unkown
HY-112129 AGI25696-analog / Unkown
HY-142928 MAT2A-IN-1 Inhibitor / Unkown
HY-142929 MAT2A-IN-2 Inhibitor / Unkown
HY-142930 MAT2A-IN-3 Inhibitor / Unkown
HY-144181 MAT2A-IN-5 Inhibitor / Unkown
HY-144184 MAT2A-IN-6 Inhibitor / Unkown
HY-144185 MAT2A-IN-7 Inhibitor / Unkown
HY-155149 MAT2A-IN-12 Inhibitor / Unkown
HY-162010 MAT2A-IN-13 Inhibitor / Unkown
HY-163799 PRMT5-MTA-IN-1 Inhibitor / Unkown
HY-168445 MAT2A-IN-21 Inhibitor / Unkown
HY-170421 MAT2A-IN-16 Inhibitor / Unkown
HY-170905S MAT2A-IN-22 Inhibitor / Unkown
HY-170906S MAT2A-IN-23 Inhibitor / Unkown
HY-172733 PRMT5-MTA-IN-3 Inhibitor / Unkown
HY-172733S PRMT5-MTA-IN-3-d3 Inhibitor / Unkown
HY-173281 MAT2A-IN-24 Inhibitor / Unkown
HY-174983 PRMT5-MTA-IN-6 Inhibitor / Unkown
HY-176702 PRMT5-MTA-IN-5 Inhibitor / Unkown
HY-179622 ZS34 / Unkown
HY-180816 PRMT5-MTA-IN-7 Inhibitor / Unkown
HY-180918 ERG-IN-4 / Unkown
HY-180919 ERG-IN-5 Inhibitor / Unkown
HY-181260 PRMT5-MTA-IN-8 / Unkown
HY-182400 AGI-25696 Inhibitor / Unkown
HY-183568 MAT2A-IN-26 Inhibitor / Unkown
HY-183951 TNG456 Inhibitor / Unkown
HY-184290 PRMT5-IN-56 / Unkown
HY-RS08749 MTAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W750643 m-APTA Substrate 99.54% Unkown
HY-RS16680 Mtap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23115 Mtap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtap NCBI NCBI:4507
Mus musculus Mtap NCBI NCBI:66902