ERG-IN-4
ERG-IN-4 (Compound 12) is an orally active, selective ERG inhibitor with an IC50 of 5.2 μM for hERG. ERG-IN-4 activates PXR. ERG-IN-4 exhibits anticancer activity against MTAP-deleted non-small cell lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 3047672-14-7
- Formula: C24H22F3N7O2
- Molecular Weight:497.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 5.2 μM for hERG[1]
Chemical Information
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CAS No. 3047672-14-7
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Molecular Weight 497.47
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Formula C24H22F3N7O2
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SMILES
CN(N=C1)C2=C1C(N)=NC3=C2C=C(C(N(N(C(C4CC4)=O)C)CC5=NC=C(C(F)(F)F)C=C5)=O)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)