2. Epigenetics Metabolic Enzyme/Protease
  3. Methionine Adenosyltransferase (MAT)
  4. MAT2A-IN-13

MAT2A-IN-13 is a potent and orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with a favorable pharmacokinetic profile. MAT2A-IN-13 shows in vivo potency in an HCT-116 MTAP-deleted xenograft model. MAT2A-IN-13 can be used for MTAP-Deleted tumors treatment research.

For research use only. We do not sell to patients.

MAT2A-IN-13 Chemical Structure

MAT2A-IN-13 Chemical Structure

CAS No. : 2851449-24-4

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MAT2A-IN-13 Related Antibodies

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Description

MAT2A-IN-13 is a potent and orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with a favorable pharmacokinetic profile. MAT2A-IN-13 shows in vivo potency in an HCT-116 MTAP-deleted xenograft model. MAT2A-IN-13 can be used for MTAP-Deleted tumors treatment research[1].

Molecular Weight

364.30

Formula

C17H12F4N4O
CAS No.
SMILES

O=C1C(C2=CC=CN=C2F)=C(C=C(C(F)(F)F)C=C3)N3C(NC4CC4)=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MAT2A-IN-13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAT2A-IN-132851449-24-4Methionine Adenosyltransferase (MAT)S-adenosylmethionine SynthetaseAG-270HCT-116MTAP-deleted xenografttumorMAT2AInhibitorinhibitorinhibit

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