MAT2A-IN-12
MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM. MAT2A Allosteric inhibitor 2 shows nanomolar activity (IC50=5 μM) in the the proliferation assay (MTAP-/- cell line).
For research use only. We do not sell to patients.
- CAS No.: 631897-75-1
- Formula: C20H17NO3
- Molecular Weight:319.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
4.957 μM
Compound: 17; STL235627
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Antiproliferative activity against MTAP-/- isogenic variant of human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
Antiproliferative activity against MTAP-/- isogenic variant of human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
|
[PMID: 37591318] |
| HCT-116 | IC50 |
9.23 μM
Compound: 17; STL235627
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
|
[PMID: 37591318] |
Chemical Information
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CAS No. 631897-75-1
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Molecular Weight 319.35
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Formula C20H17NO3
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SMILES
CC1=CC(OC2=C3C=C(OC)C=C2)=C3C(C4=CC=C(C)C=C4)=[N+]1[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAT2A-IN-12 Related Classifications
HY-155149 Related Classifications
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