Mtap - methylthioadenosine phosphorylase Gene

Also Known as MSAP; 1300019I21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66902

Summary

Predicted to enable S-methyl-5-thioadenosine Phosphorylase activity. Acts upstream of or within methylation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine Phosphorylase). [provided by Alliance of Genome Resources, Apr 2022]

Mtap Products (1)

mRNA Protein Name
NM_024433.2 NP_077753.1 S-methyl-5'-thioadenosine phosphorylase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within methylation IMP
IMP: Inferred from mutant phenotype
22952318 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

S-methyl-5'-thioadenosine phosphorylase

  • 5'-methylthioadenosine phosphorylase

  • MTA phosphorylase

  • MTAPase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-156680 Vopimetostat Inhibitor 99.55% Phase 2
HY-148419 Ralometostat Inhibitor 99.90% Phase 2
HY-16933 L-Alanosine Inhibitor 99.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (44)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153390 AMG-193 Inhibitor 99.71% Unkown
HY-101496 MT-DADMe-ImmA Inhibitor 99.17% Unkown
HY-112130 AGI-24512 Inhibitor 99.46% Unkown
HY-145778 AGI-41998 Inhibitor 98.72% Unkown
HY-162353 AZ'9567 99.19% Unkown
HY-145777 AGI-43192 Inhibitor 99.47% Unkown
HY-138684 MRTX9768 Inhibitor 99.60% Unkown
HY-153390A (R)-AMG-193 Inhibitor 98.72% Unkown
HY-158143 AZD3470 99.74% Unkown
HY-162783 AZ-PRMT5i-1 Inhibitor / Unkown
HY-138684A MRTX9768 hydrochloride Inhibitor 99.88% Unkown
HY-112129 AGI25696-analog / Unkown
HY-142928 MAT2A-IN-1 Inhibitor / Unkown
HY-142929 MAT2A-IN-2 Inhibitor / Unkown
HY-142930 MAT2A-IN-3 Inhibitor / Unkown
HY-144181 MAT2A-IN-5 Inhibitor / Unkown
HY-144184 MAT2A-IN-6 Inhibitor / Unkown
HY-144185 MAT2A-IN-7 Inhibitor / Unkown
HY-155149 MAT2A-IN-12 Inhibitor / Unkown
HY-162010 MAT2A-IN-13 Inhibitor / Unkown
HY-163799 PRMT5-MTA-IN-1 Inhibitor / Unkown
HY-168445 MAT2A-IN-21 Inhibitor / Unkown
HY-170421 MAT2A-IN-16 Inhibitor / Unkown
HY-170905S MAT2A-IN-22 Inhibitor / Unkown
HY-170906S MAT2A-IN-23 Inhibitor / Unkown
HY-172733 PRMT5-MTA-IN-3 Inhibitor / Unkown
HY-172733S PRMT5-MTA-IN-3-d3 Inhibitor / Unkown
HY-173281 MAT2A-IN-24 Inhibitor / Unkown
HY-174983 PRMT5-MTA-IN-6 Inhibitor / Unkown
HY-176702 PRMT5-MTA-IN-5 Inhibitor / Unkown
HY-179622 ZS34 / Unkown
HY-180816 PRMT5-MTA-IN-7 Inhibitor / Unkown
HY-180918 ERG-IN-4 / Unkown
HY-180919 ERG-IN-5 Inhibitor / Unkown
HY-181260 PRMT5-MTA-IN-8 / Unkown
HY-182400 AGI-25696 Inhibitor / Unkown
HY-183568 MAT2A-IN-26 Inhibitor / Unkown
HY-183951 TNG456 Inhibitor / Unkown
HY-184290 PRMT5-IN-56 / Unkown
HY-184434 PRMT5-IN-57 Inhibitor / Unkown
HY-RS08749 MTAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W750643 m-APTA Substrate 99.54% Unkown
HY-RS16680 Mtap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23115 Mtap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtap NCBI NCBI:4507