Mlph - melanophilin Gene

Predicted to enable cytoskeletal protein binding activity; protein-macromolecule adaptor activity; and small GTPase binding activity. Predicted to act upstream of or within melanocyte differentiation; melanosome localization; and protein targeting. Predicted to be located in several cellular components, including cytoskeleton; melanosome; and perinuclear region of cytoplasm. Predicted to be part of unconventional Myosin complex. Predicted to be active in cortical actin Cytoskeleton. Human ortholog(s) of this gene implicated in Griscelli syndrome type 3. Orthologous to human MLPH (melanophilin). [provided by Alliance of Genome Resources, Apr 2022]