HRNR - hornerin Gene

Also Known as FLG3; S100A16; S100a18

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 388697

About HRNR

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:152,212,076-152,224,193 (from NCBI)

This gene has 1 transcript (splice variant), 39 orthologues and 3 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable calcium ion binding activity and transition metal ion binding activity. Involved in cell envelope organization and establishment of skin barrier. Located in cornified envelope; keratohyalin granule; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HRNR Products (1)

mRNA Protein Name
NM_001009931.3 NP_001009931.1 hornerin

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence 参考文献 由来
involved in cell envelope organization IDA
IDA: Inferred from direct assay
21282207 GOA
involved in establishment of skin barrier IEP
IEP: Inferred from expression pattern
23403047 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in cornified envelope IDA
IDA: Inferred from direct assay
21282207 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
21282207 GOA
located in keratohyalin granule IDA
IDA: Inferred from direct assay
21282207 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
21282207 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HRNR Protein Structure

S_100

S_100: S-100/ICaBP type calcium binding domain (4 - 47)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2850 a.a.
Protein Preferred Names Protein Names

hornerin

  • filaggrin family member 3

関連疾患

Diseases Alias
Ichthyosis Vulgaris

  • Ichthyosis Simplex

  • Dominant Congenital Ichthyosiform Erythroderma

  • Common Ichthyosis

  • Fish Scale Disease

  • VI

  • Ichthyoses

  • Congenital Ichthyosis
Autosomal Recessive Congenital Ichthyosis

  • Lamellar Ichthyosis

  • Congenital Ichthyosiform Erythroderma

  • Li

  • Congenital Nonbullous Ichthyosiform Erythroderma

  • Arci

  • Congenital Lamellar Ichthyosis

  • Nonbullous Congenital Ichthyosiform Erythroderma

  • Cie

  • Congenital Non-Bullous Ichthyosiform Erythroderma

  • Erythrodermic Ichthyosis

  • Nbcie

  • Ncie

  • Non-Bullous Congenital Ichthyosiform Erythroderma

  • Collodion Baby

  • Ichthyosis, Lamellar

  • Non Bullous Congenital Ichthyosiform Erythroderma

  • Ichthyosiform Erythroderma, Brocq Congenital, Nonbullous Form

  • Ichthyosiform Erythroderma, Congenital, Nonbullous, 1

  • Collodion Baby Syndrome

  • Ichthyoses, Lamellar

  • Nbie

  • Nonbullous Ichthyosiform Erythroderma

  • Classic Lamellar Ichthyosis

  • Ichthyosiform Erythroderma Nonbullous Congenital

  • Ichthyosiform Erythroderma Congenital

  • Ichthyosis, Congenital, Autosomal Recessive

  • Ichthyosiform Erythroderma, Congenital

  • Collodion Fetus

  • Non-Bullous Ichthyosiform Erythroderma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS06372 HRNR Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus HRNR RGD RGD:1307660
Mus musculus HRNR MGD MGI:3046938
Felis catus HRNR VGNC VGNC:107561
Others HRNR NCBI