FRRS1 - ferric chelate reductase 1 Gene

Also Known as SDR2; SDFR2

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 391059

About FRRS1

Cytogenetic location: 1p21.2 Genomic coordinates (GRCh38): 1:99,703,970-99,766,635 (from NCBI)

This gene has 5 transcripts (splice variants), 224 orthologues and 2 paralogues. Broad expression in liver (RPKM 6.9), placenta (RPKM 5.3) and 22 other tissues.

Summary

Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]

FRRS1 Products (2)

mRNA Protein Name
NM_001013660.4 NP_001013682.2 ferric-chelate reductase 1 isoform 1 precursor
NM_001361041.2 NP_001347970.1 ferric-chelate reductase 1 isoform 2 precursor

FRRS1 Protein Structure

Reeler

Reeler: Reeler domain (31 - 156)

DOMON

DOMON: DOMON domain (217 - 331)

  • 0
  • 100
  • 200
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  • 500
  • 626 a.a.
Protein Preferred Names Protein Names

ferric-chelate reductase 1

  • SDR-2

関連疾患

Diseases Alias
Lice Infestation

  • Pediculosis

  • Louse Infestation

  • Mixed Pediculosis

  • Lice Infestations

  • Infestation By Pediculus

  • Mixed Pediculosis Infestation

  • Pediculosis + Lice

  • Pediculosis And Phthirus Infection

  • Pediculosis And Phthirus Infections

  • Pediculosis And Phthirus Infestation

  • Infestation By Anoplura

  • Pediculus Infestation

  • Lice Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05110 FRRS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05111 FRRS1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus FRRS1 VGNC VGNC:62367
Canis familiaris FRRS1 VGNC VGNC:40985
Rattus norvegicus FRRS1 RGD RGD:1306883
Macaca mulatta FRRS1 VGNC VGNC:72795
Mus musculus FRRS1 MGD MGI:108076
Others FRRS1 NCBI