PCDH9 - protocadherin 9 Gene
生物種: Homo sapiens
About PCDH9
This gene has 6 transcripts (splice variants), 220 orthologues and 33 paralogues. Biased expression in brain (RPKM 8.9), fat (RPKM 0.9) and 2 other tissues.
Summary
This gene encodes a member of the protocadherin family, and Cadherin superfamily, of transmembrane proteins containing Cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple Cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
PCDH9 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001318372.2 | NP_001305301.1 | protocadherin-9 isoform 3 precursor |
| NM_001318373.2 | NP_001305302.1 | protocadherin-9 isoform 4 precursor |
| NM_001318374.2 | NP_001305303.1 | protocadherin-9 isoform 5 precursor |
| NM_020403.5 | NP_065136.1 | protocadherin-9 isoform 2 precursor |
| NM_203487.3 | NP_982354.1 | protocadherin-9 isoform 1 precursor |
PCDH9 Protein Structure
Cadherin_2: Cadherin-like (26 - 117)
Cadherin: Cadherin domain (148 - 242)
Cadherin: Cadherin domain (259 - 349)
Cadherin: Cadherin domain (371 - 459)
Cadherin: Cadherin domain (476 - 563)
Cadherin: Cadherin domain (578 - 665)
Cadherin: Cadherin domain (693 - 763)
Protocadherin: Protocadherin (777 - 1002)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1237 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protocadherin-9 |
|
PCDH9 抗体
| 製品番号 | 製品名 | アプリケーション | 反応性 |
|---|---|---|---|
| HY-P84808 | PCDH9 Antibody (YA4505) | WB, ICC/IF, FC, ELISA | Human |
| HY-P84808A | PCDH9 Antibody (YA4505)(PBS only) | WB, ICC/IF, FC, ELISA | Human |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Auditory Neuropathy, Autosomal Dominant 1 |
|
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| Developmental And Epileptic Encephalopathy 9 |
|
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| Ehlers-Danlos Syndrome, Hypermobility Type |
|
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Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Mus musculus | PCDH9 | MGD | MGI:1306801 |
| Rattus norvegicus | PCDH9 | RGD | RGD:1306348 |
| Canis familiaris | PCDH9 | VGNC | VGNC:49937 |
| Felis catus | PCDH9 | VGNC | VGNC:68719 |
| Macaca mulatta | PCDH9 | VGNC | VGNC:75778 |
| Others | PCDH9 | NCBI |