RNFT1 - ring finger protein, transmembrane 1 Gene

Also Known as PTD016

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 51136

About RNFT1

Cytogenetic location: 17q23.1 Genomic coordinates (GRCh38): 17:59,952,240-59,964,740 (from NCBI)

This gene has 9 transcripts (splice variants), 208 orthologues and 1 paralogue. Broad expression in testis (RPKM 54.5), appendix (RPKM 8.9) and 22 other tissues.

Summary

Enables ubiquitin binding activity and ubiquitin protein Ligase activity. Involved in positive regulation of ERAD pathway and protein autoubiquitination. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

RNFT1 Products (1)

mRNA Protein Name
NM_016125.4 NP_057209.3 E3 ubiquitin-protein ligase RNFT1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables ubiquitin binding IDA
IDA: Inferred from direct assay
27485036 GOA
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
27485036 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of ERAD pathway IMP
IMP: Inferred from mutant phenotype
27485036 GOA
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
27485036 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
27485036 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RNFT1 Protein Structure

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (372 - 418)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 435 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNFT1

  • RING finger and transmembrane domain-containing protein 1

関連疾患

Diseases Alias
Papillary Cystadenocarcinoma

  • Cystadenocarcinoma, Papillary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS12098 RNFT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus RNFT1 VGNC VGNC:34074
Mus musculus RNFT1 MGD MGI:1924142
Canis familiaris RNFT1 VGNC VGNC:45677
Felis catus RNFT1 VGNC VGNC:64707
Rattus norvegicus RNFT1 RGD RGD:1562411
Macaca mulatta RNFT1 VGNC VGNC:76865
Others RNFT1 NCBI