SERPINB10 - serpin family B member 10 Gene

Also Known as PI10; PI-10

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 5273

About SERPINB10

Cytogenetic location: 18q22.1 Genomic coordinates (GRCh38): 18:63,907,958-63,936,111 (from NCBI)

This gene has 1 transcript (splice variant), 122 orthologues and 36 paralogues. Restricted expression toward bone marrow (RPKM 23.0).

Summary

This gene is a member of the Serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of Protease functions during hematopoiesis. Variations in this gene may increase the risk of Prostate Cancer. [provided by RefSeq, Dec 2015]

SERPINB10 Products (1)

mRNA Protein Name
NM_005024.3 NP_005015.1 serpin B10

SERPINB10 Protein Structure

Serpin

Serpin: Serpin (serine protease inhibitor) (7 - 397)

  • 0
  • 100
  • 200
  • 300
  • 397 a.a.
Protein Preferred Names Protein Names

serpin B10

  • bomapin

関連疾患

Diseases Alias
Tracheal Calcification
  • Calcification Of Trachea

Chronic Myelomonocytic Leukemia
  • Leukemia, Myelomonocytic, Chronic

  • Cmml

  • Leukemia Myelomonocytic Chronic

  • Cmml - [Chronic Myelomonocytic Leukaemia]

  • Chronic Myelomonocytic Leukaemia Without Mention Of Remission

  • Chronic Monocytic Leukaemia

  • Chronic Monocytoid Leukaemia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus SERPINB10 RGD RGD:628853
Canis familiaris SERPINB10 VGNC VGNC:46027
Felis catus SERPINB10 VGNC VGNC:68833
Mus musculus SERPINB10 MGD MGI:2138648
Macaca mulatta SERPINB10 VGNC VGNC:77365
Bos taurus SERPINB10 VGNC VGNC:56372
Others SERPINB10 NCBI