Cfhr2 - complement factor H-related 2 Gene

Also Known as FHR-B; Cfhrb_4/2

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 545366

Summary

Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in age related macular degeneration 1 and atypical hemolytic-uremic syndrome. Orthologous to several human genes including CFHR3 (Complement Factor H Related 3). [provided by Alliance of Genome Resources, Apr 2022]

Cfhr2 Products (1)

mRNA Protein Name
NM_001025575.2 NP_001020746.1 complement factor H-related protein B precursor
Molecular Function GO Annotation Evidence 参考文献 由来
enables complement component C3b binding IPI
IPI: Inferred from physical interaction
17028856 MGI
enables heparin binding IDA
IDA: Inferred from direct assay
17028856 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in extracellular space IDA
IDA: Inferred from direct assay
17028856 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement factor H-related protein B

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Cfhr2 NCBI NCBI:3080