BSPRY - B-box and SPRY domain containing Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 54836

About BSPRY

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:113,349,541-113,371,222 (from NCBI)

This gene has 2 transcripts (splice variants), 119 orthologues and 80 paralogues. Broad expression in thyroid (RPKM 21.8), salivary gland (RPKM 19.5) and 16 other tissues.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in cell leading edge; membrane; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

BSPRY Products (3)

mRNA Protein Name
NM_001317943.2 NP_001304872.1 B box and SPRY domain-containing protein isoform 1
NM_001317944.2 NP_001304873.1 B box and SPRY domain-containing protein isoform 3
NM_017688.3 NP_060158.2 B box and SPRY domain-containing protein isoform 2

BSPRY Protein Structure

zf-B_box

zf-B_box: B-box zinc finger (20 - 57)

PRY

PRY: SPRY-associated domain (234 - 281)

SPRY

SPRY: SPRY domain (284 - 397)

  • 0
  • 100
  • 200
  • 300
  • 402 a.a.
Protein Preferred Names Protein Names

B box and SPRY domain-containing protein

  • B-box and SPRY-domain containing protein

関連疾患

Diseases Alias
Kleefstra Syndrome 1

  • 9q Subtelomeric Deletion Syndrome

  • KLEFS1

  • Chromosome 9q34.3 Deletion Syndrome

  • 9q- Syndrome

  • 9q34 Deletion Syndrome

  • Kleefstra Syndrome Due To 9q34 Microdeletion

  • Kleefstra Syndrome

  • 9q-Syndrome

  • 9qstds

  • Kleefstra Syndrome Due To 9q Subtelomeric Deletion

  • Kleefstra Syndrome Due To Del(9)(Q34)

  • Kleefstra Syndrome Due To Monosomy 9q34

  • Chromosome 9q Subtelomeric Deletion Syndrome

  • Kleefstra Syndrome, Type 1
Parathyroid Adenoma

  • Adenoma Of Parathyroid

  • Adenoma Of The Parathyroid Gland

  • Parathyroid Gland Adenoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS01647 BSPRY Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus BSPRY MGD MGI:2177191
Canis familiaris BSPRY VGNC VGNC:49718
Felis catus BSPRY VGNC VGNC:60190
Macaca mulatta BSPRY VGNC VGNC:70342
Rattus norvegicus BSPRY RGD RGD:708400
Bos taurus BSPRY VGNC VGNC:26580
Others BSPRY NCBI