NOL8 - nucleolar protein 8 Gene

Also Known as NOP132; C9orf34; bA62C3.3; bA62C3.4

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 55035

About NOL8

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:92,297,358-92,325,350 (from NCBI)

This gene has 29 transcripts (splice variants) and 225 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), appendix (RPKM 6.7) and 25 other tissues.

Summary

NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008]

NOL8 Products (3)

mRNA Protein Name
NM_001256394.2 NP_001243323.1 nucleolar protein 8 isoform b
NM_001330722.2 NP_001317651.1 nucleolar protein 8 isoform c
NM_017948.6 NP_060418.4 nucleolar protein 8 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
11073942 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in protein localization to nucleolus IMP
IMP: Inferred from mutant phenotype
16963496 GOA
involved in rRNA processing IMP
IMP: Inferred from mutant phenotype
16963496 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in nucleolus IDA
IDA: Inferred from direct assay
14660641 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NOL8 Protein Structure

(10 - 82)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1167 a.a.
Protein Preferred Names Protein Names

nucleolar protein 8

  • nucleolar protein Nop132

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09418 NOL8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus NOL8 VGNC VGNC:106844
Rattus norvegicus NOL8 RGD RGD:1309551
Mus musculus NOL8 MGD MGI:1918180
Macaca mulatta NOL8 VGNC VGNC:75237
Felis catus NOL8 VGNC VGNC:63853
Canis familiaris NOL8 VGNC VGNC:54850
Others NOL8 NCBI