RABEP2 - rabaptin, RAB GTPase binding effector protein 2 Gene

Also Known as FRA

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 79874

About RABEP2

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,904,421-28,925,238 (from NCBI)

This gene has 14 transcripts (splice variants), 182 orthologues and 1 paralogue. Ubiquitous expression in prostate (RPKM 13.2), spleen (RPKM 11.9) and 25 other tissues.

Summary

Predicted to enable GTPase activator activity and growth factor activity. Involved in regulation of cilium assembly. Located in cytosol; intracellular membrane-bounded organelle; and microtubule organizing center. [provided by Alliance of Genome Resources, Apr 2022]

RABEP2 Products (1)

mRNA Protein Name
NM_024816.3 NP_079092.2 rab GTPase-binding effector protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
27224062 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
27224062 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in centrosome IDA
IDA: Inferred from direct assay
27224062 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
27224062 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RABEP2 Protein Structure

Rabaptin

Rabaptin: Rabaptin (58 - 163)

Rabaptin

Rabaptin: Rabaptin (257 - 347)

Rab5-bind

Rab5-bind: Rabaptin-like protein (347 - 514)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 569 a.a.
Protein Preferred Names Protein Names

rab GTPase-binding effector protein 2

  • Rabaptin-5 beta

RABEP2 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
RABEP2 Q9H5N1 SDCCAG8 Homo sapiens Q86SQ7
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

RABEP2 抗体

製品番号 製品名 アプリケーション 反応性
HY-P84801 RABEP2 Antibody (YA4498) IHC-P, FC, ELISA Human
HY-P84801A RABEP2 Antibody (YA4498)(PBS only) IHC-P, FC, ELISA Human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11583 RABEP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris RABEP2 VGNC VGNC:45301
Mus musculus RABEP2 MGD MGI:1917564
Bos taurus RABEP2 VGNC VGNC:33668
Felis catus RABEP2 VGNC VGNC:64474
Rattus norvegicus RABEP2 RGD RGD:621416
Macaca mulatta RABEP2 VGNC VGNC:76531
Others RABEP2 NCBI