Hacl1 - 2-hydroxyacyl-CoA lyase 1 Gene

Also Known as Hpcl2; Phyh2

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 85255

Summary

Enables carbon-carbon lyase activity and thiamine pyrophosphate binding activity. Involved in fatty acid alpha-oxidation and methyl-branched fatty acid metabolic process. Located in peroxisome. Orthologous to human HACL1 (2-hydroxyacyl-CoA lyase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hacl1 Products (1)

mRNA Protein Name
NM_053493.1 NP_445945.1 2-hydroxyacyl-CoA lyase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables carbon-carbon lyase activity IDA
IDA: Inferred from direct assay
10468558 RGD
enables thiamine pyrophosphate binding IDA
IDA: Inferred from direct assay
10468558 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in fatty acid alpha-oxidation IDA
IDA: Inferred from direct assay
10468558 RGD
involved in methyl-branched fatty acid metabolic process IDA
IDA: Inferred from direct assay
10468558 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in peroxisome IDA
IDA: Inferred from direct assay
10468558 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2-hydroxyacyl-CoA lyase 1

  • 2-HPCL

  • 2-hydroxyphytanoyl-CoA lyase

  • 2-hydroxyphytanoyl-Coenzyme A lyase

  • phytanoyl-CoA 2-hydroxylase 2

  • phytanoyl-Coenzyme A 2-hydroxylase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05988 HACL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22547 Hacl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29067 Hacl1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Hacl1 NCBI NCBI:26061