ZMYM5 - zinc finger MYM-type containing 5 Gene

Also Known as MYM; ZNF237; HSPC050; ZNF198L1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 9205

About ZMYM5

Cytogenetic location: 13q12.11 Genomic coordinates (GRCh38): 13:19,823,482-19,863,649 (from NCBI)

This gene has 7 transcripts (splice variants), 84 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 10.0), gall bladder (RPKM 4.8) and 25 other tissues.

Summary

Predicted to enable zinc ion binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZMYM5 Products (3)

mRNA Protein Name
NM_001039649.3 NP_001034738.1 zinc finger MYM-type protein 5 isoform 2
NM_001039650.3 NP_001034739.1 zinc finger MYM-type protein 5 isoform 1
NM_001142684.2 NP_001136156.1 zinc finger MYM-type protein 5 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
17126306 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17126306 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZMYM5 Protein Structure

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (241 - 276)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (333 - 369)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (373 - 415)

  • 0
  • 200
  • 400
  • 600
  • 669 a.a.
Protein Preferred Names Protein Names

zinc finger MYM-type protein 5

  • zinc finger protein 198-like 1

関連疾患

Diseases Alias
Dyskeratosis Congenita, Autosomal Recessive 2

  • DKCB2

  • Autosomal Recessive Dyskeratosis Congenita 2

  • Dyskeratosis Congenita, Autosomal Recessive, 2

  • Dyskeratosis Congenita, Autosomal Recessive, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS16092 ZMYM5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus ZMYM5 VGNC VGNC:67261
Bos taurus ZMYM5 VGNC VGNC:56647
Mus musculus ZMYM5 MGD MGI:3041170
Rattus norvegicus ZMYM5 RGD RGD:1306353
Macaca mulatta ZMYM5 VGNC VGNC:78880
Others ZMYM5 NCBI