WDR46 - WD repeat domain 46 Gene

Also Known as UTP7; BING4; FP221; C6orf11

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 9277

About WDR46

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:33,279,108-33,289,239 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele and 188 orthologues. Ubiquitous expression in appendix (RPKM 10.6), testis (RPKM 10.3) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

WDR46 Products (2)

mRNA Protein Name
NM_001164267.2 NP_001157739.1 WD repeat-containing protein 46 isoform 2
NM_005452.6 NP_005443.3 WD repeat-containing protein 46 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence 参考文献 由来
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WDR46 Protein Structure

WD40

WD40: WD domain, G-beta repeat (350 - 387)

BING4CT

BING4CT: BING4CT (NUC141) domain (440 - 518)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 610 a.a.
Protein Preferred Names Protein Names

WD repeat-containing protein 46

  • WD repeat-containing protein BING4

関連疾患

Diseases Alias
Asthma, Nasal Polyps, And Aspirin Intolerance

  • Asthma And Nasal Polyps

  • Asa Triad

  • Asthma, Aspirin-Induced, Susceptibility To

  • Asthma, Aspirin-Induced

  • Asthma, With Nasal Polyps And Aspirin Intolerance

  • ANPAI

  • Aia

  • Aspirin-Intolerant Asthma

  • Asthma Aspirin-Induced

  • Nasal Polyps Asthma And Aspirin Sensitivity

  • Samter Triad

  • Asthma With Aspirin Triad Including Nonsteroidal Anti-Inflammatory Activity And Nasal Polyps
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS15782 WDR46 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta WDR46 VGNC VGNC:78940
Rattus norvegicus WDR46 RGD RGD:2209
Mus musculus WDR46 MGD MGI:1931871
Felis catus WDR46 VGNC VGNC:67036
Canis familiaris WDR46 VGNC VGNC:48369
Bos taurus WDR46 VGNC VGNC:36902
Others WDR46 NCBI