hCA-IN-1
hCA-IN-1 (Compound 5u) is an hCA inhibitor with Ki values of 159.2, 4.8, 15.5, and 2 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. hCA-IN-1 exhibits broad-spectrum anticancer activity against melanoma, breast, and colon cancer cells. ADME predictions indicate that hCA-IN-1 has good solubility and oral bioavailability. hCA-IN-1 can be used in tumor research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C20H18N4O4S3
- 分子量:474.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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hCA I 159.2 nM (Ki) |
hCA II 4.8 nM (Ki) |
hCA IX 15.5 nM (Ki) |
hCA XII 2 nM (Ki) |
化学情報
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分子量 474.58
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分子式 C20H18N4O4S3
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SMILES
O=C(C(SC(SCC(NC1=CC=C(S(=O)(N)=O)C=C1)=O)=N2)=C2C)/C=C/C3=NC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)