PDE4-IN-10
PDE4-IN-10 (compound 7a) is a potent PDE4 inhibitor, with an IC50 of 7.01 μM for PDE4B. PDE4-IN-10 shows selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro.
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- CAS 番号: 2413564-66-4
- 分子式: C18H13N
- 分子量:243.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PDE4B 7.01 ± 1.0 μM (IC50) |
PDE4D |
PDE4-IN-10 (compound 7a) shows 64.56% inhibition at 10 µM against PDE4B, 54% inhibition at 30 µM but 17% inhibition at 10 µM against PDE4D, indicating its selectivity (~3.8 fold) towards PDE4B over PDE4D[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2413564-66-4
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分子量 243.30
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分子式 C18H13N
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SMILES
CC1=CC2=C3C=CC=CC3=CN=C2C4=CC=CC=C14
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PDE4-IN-10 関連分類
HY-147950 関連分類
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