2413564-66-4
2413564-66-4
Chemical Structure
PDE4-IN-10
- CAS No.: 2413564-66-4
- Formula:C18H13N
- Molecular Weight:243.30
IUPAC Name: 12-methylbenzo[c]phenanthridine
InChIKey: NKJQQWICZMKQMY-UHFFFAOYSA-N
SMILES: CC1=CC2=C3C=CC=CC3=CN=C2C4=CC=CC=C14
Biological Activity: PDE4-IN-10 (compound 7a) is a potent PDE4 inhibitor, with an IC50 of 7.01 μM for PDE4B. PDE4-IN-10 shows selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro[1].
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PDE4-IN-10 | PDE4-IN-10 (compound 7a) is a potent PDE4 inhibitor, with an IC50 of 7.01 μM for PDE4B. PDE4-IN-10 shows selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro. | |||||||||||||||||||||
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References
Keywords
