Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
Optical activity
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "Optical activity" in MCE Product Catalog:
2
Category:
Alkaloids Piperidine Alkaloids Leguminosae Pyridine Alkaloids Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
別名: (R)-Enitociclib; (-)-BAY-1251152; (-)-VIP152
Target:
研究分野:
(-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC + lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
1
Target:
Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
1
Target:
研究分野:
(S)-Lisofylline ((S)-Lisophylline)) is a kind of lisofline (LSF) enantiomer with optical activity. (S)-Lisofylline can interconversion with pentoxifylline .
製品番号: HY-W017277
CAS 番号: 15356-60-2
別名: D-Menthol
Category:
Target:
製品番号: HY-W012669
CAS 番号: 643-79-8
別名: Phthaldialdehyde
製品番号: HY-D1435
CAS 番号: 64724-75-0
Target:
製品番号: HY-W016568
CAS 番号: 529-69-1
Target:
製品番号: HY-W142092
CAS 番号: 97-14-3
Target:
研究分野:
製品番号: HY-D1460
CAS 番号: 134869-04-8
Target:
Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
製品番号: HY-Z15823
CAS 番号: 38321-02-7
別名: Dexverapamil
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil (HY-14275). (R)-Verapamil has a relatively low affinity for L-type calcium channels (Cav1.2) (IC50 > 300 μM), and its IC50 for sodium channels (sodium channel) is 3.19 μM. (R)-Verapamil exhibits SSTR2 agonistic activity, with an EC50 of 1.3 μM. (R)-Verapamil significantly downregulates the expression of TXNIP protein in diabetic mouse models and significantly inhibits β-cell apoptosis (apoptosis), effectively controlling blood sugar. (R)-Verapamil can be used as a PET tracer for the function of P-glycoprotein (P-gp) .
製品番号: HY-109854S
CAS 番号: 1268605-91-9
別名: (S)-Lisophylline-d5
製品番号: HY-125700
CAS 番号: 74239-84-2
別名: (-)-Bao Gong Teng A
Target:
製品番号: HY-171002
Target:
研究分野:
PAD2-IN-2 (cis-isomer of 1) is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 inhibits histone H3-citrullination .
製品番号: HY-171002A
Target:
研究分野:
PAD2-IN-2 (cis-isomer of 1) TFA is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 TFA possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 TFA inhibits histone H3-citrullination .
製品番号: HY-W017277R
CAS 番号: 15356-60-2
別名: D-Menthol (Standard)
Category:
Target:
Category:
Alkaloids Piperidine Alkaloids Leguminosae Pyridine Alkaloids Plants Sophora flavescens Aiton
Target:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
