529-69-1
529-69-1
Chemical Structure
Isoxanthopterin
- CAS No.: 529-69-1
- Formula:C6H5N5O2
- Molecular Weight:179.14
IUPAC Name: 2-imino-1,2-dihydropteridine-4,7-diol
InChIKey: GLKCOBIIZKYKFN-UHFFFAOYSA-N
SMILES: O=C1C(N=C2)=C(NC(N)=N1)NC2=O
Biological Activity: Isoxanthopterin is a pteridine marker used to indicate xanthine oxidase activity. Isoxanthopterin is used in research on type 1 diabetes, breast cancer, and hyperphenylalaninemia[1][2][3][4][5][6][7].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isoxanthopterin | 99.85% | Isoxanthopterin is a pteridine marker used to indicate xanthine oxidase activity. Isoxanthopterin is used in research on type 1 diabetes, breast cancer, and hyperphenylalaninemia. | ||||||||||||||||||||
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References
- [1]. Özer Y, et al. Pteridine and tryptophan pathways in children with type 1 diabetes: Isoxanthopterin as an indicator of endothelial dysfunction. Journal of pharmaceutical and biomedical analysis. 2024 Jun 15;243:116072.
- [2]. Hirsch A, et al. Structure and Morphology of Light‑Reflecting Synthetic and Biogenic Polymorphs of Isoxanthopterin: A Comparison. *Chem Mater*. 2019;31(12):4479‑4489.
- [3]. Prabavathi N, et al. Vibrational spectroscopic (FT-IR and FT-Raman) studies, natural bond orbital analysis and molecular electrostatic potential surface of Isoxanthopterin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2013 Oct;114:101-13.
- [4]. Palmer BA, et al. Optically functional isoxanthopterin crystals in the mirrored eyes of decapod crustaceans. Proceedings of the National Academy of Sciences of the United States of America. 2018 Mar 06;115(10):2299-2304.
- [5]. MCNUTT WS Jr. The metabolism of isoxanthopterin by Alcaligenes faecalis. J Biol Chem. 1963 Mar;238:1116-21.
- [6]. Bao PZ, et al. Application of isoxanthopterin as a new pterin marker in the differential diagnosis of hyperphenylalaninemia. World journal of pediatrics : WJP. 2019 Feb;15(1):66-71.
- [7]. Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer letters. 2005 May 10;222(1):119-24. [Content Brief]
