Skatole-d3
Based on 1 Customer Validation
Skatole-d3 is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.10%
- CAS 番号: 111399-60-1
- 分子式: C9H6D3N
- 分子量:134.19
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 111399-60-1
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非標識Cas 83-34-1
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性状 Solid
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分子量 134.19
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分子式 C9H6D3N
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Color White to off-white
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SMILES
[2H]C(C1=CNC2=C1C=CC=C2)([2H])[2H]
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別名
3-Methylindole-d3; 3-Methyl-1H-indole-d3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (745.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kurata K, et al. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. Biochem Biophys Res Commun. 2019 Mar 19;510(4):649-655. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4521 mL | 37.2606 mL | 74.5212 mL | 186.3030 mL |
| 5 mM | 1.4904 mL | 7.4521 mL | 14.9042 mL | 37.2606 mL | |
| 10 mM | 0.7452 mL | 3.7261 mL | 7.4521 mL | 18.6303 mL | |
| 15 mM | 0.4968 mL | 2.4840 mL | 4.9681 mL | 12.4202 mL | |
| 20 mM | 0.3726 mL | 1.8630 mL | 3.7261 mL | 9.3151 mL | |
| 25 mM | 0.2981 mL | 1.4904 mL | 2.9808 mL | 7.4521 mL | |
| 30 mM | 0.2484 mL | 1.2420 mL | 2.4840 mL | 6.2101 mL | |
| 40 mM | 0.1863 mL | 0.9315 mL | 1.8630 mL | 4.6576 mL | |
| 50 mM | 0.1490 mL | 0.7452 mL | 1.4904 mL | 3.7261 mL | |
| 60 mM | 0.1242 mL | 0.6210 mL | 1.2420 mL | 3.1050 mL | |
| 80 mM | 0.0932 mL | 0.4658 mL | 0.9315 mL | 2.3288 mL | |
| 100 mM | 0.0745 mL | 0.3726 mL | 0.7452 mL | 1.8630 mL |
Skatole-d3 関連分類
HY-W007355S 関連分類
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