UA2239
UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2455422-89-4
- 分子式: C9H12N5Na2O5P
- 分子量:347.18
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Plasmodium |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
1000 μM
Compound: (R)-5
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Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
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[PMID: 32687714] |
化学情報
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CAS 番号 2455422-89-4
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分子量 347.18
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分子式 C9H12N5Na2O5P
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SMILES
O=C1NC(N)=NC2=C1N=CN2CC[C@H](CP(O[Na])(O[Na])=O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UA2239 関連分類
HY-179656 関連分類
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