TMED7 - transmembrane p24 trafficking protein 7 Gene

Also Known as Tag; p27; p24g3; CGI-109; p24gamma3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51014

About TMED7

Cytogenetic location: 5q22.3 Genomic coordinates (GRCh38): 5:115,613,210-115,626,036 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 8 paralogues. Ubiquitous expression in thyroid (RPKM 58.5), endometrium (RPKM 47.2) and 25 other tissues.

Summary

Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]

TMED7 Products (1)

mRNA Protein Name
NM_181836.6 NP_861974.1 transmembrane emp24 domain-containing protein 7 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12237308 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12237308 GOA
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
10359607 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMED7 Protein Structure

EMP24_GP25L

EMP24_GP25L: emp24/gp25L/p24 family/GOLD (37 - 212)

  • 0
  • 100
  • 200
  • 224 a.a.
Protein Preferred Names Protein Names

transmembrane emp24 domain-containing protein 7

  • p24 family protein gamma-3

TMED7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMED7 Q9Y3B3 PA2G4 Homo sapiens Q9UQ80
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14639 TMED7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TMED7 MGD MGI:1913926
Bos taurus TMED7 VGNC VGNC:55150
Rattus norvegicus TMED7 RGD RGD:727954
Others TMED7 NCBI