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Isoprenaline hydrochloride

(Synonyms: Isoproterenol hydrochloride)
89 Cited Publications
고객리뷰

Based on 89 publication(s) in Google Scholar

Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma.

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  • Purity: 99.86%
  • CAS No.: 51-30-9
  • 화학식: C11H18ClNO3
  • 분자량:247.72
  • 보관:

    4°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • Isoprenaline hydrochloride Chemical Structure
    Isoprenaline hydrochloride Chemical Structure
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
  • Experimental Validation Results for Isoprenaline hydrochloride
CAS No.: 51-30-9
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  • Isoprenaline hydrochloride Chemical Structure
    Isoprenaline hydrochloride Chemical Structure
    1/16
  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2024 Sep 1.

    Customer Validation
     Isoprenaline administration significantly reduces [email protected] anti-inflammatory and antioxidant activities.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2024 Sep 1.

    Customer Validation
     Isoprenaline significantly activates ERK1/2-induced DRP1 phosphorylation on serine 616 (pDRP1).

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2023 Feb;20(2):175-188. [Abstract]

    Customer Validation
     Isoprenaline hydrochloride (ISO; 10 μM; 6 h), markedly inhibits SeV- or HSV-1-induced transcription of the IFNB1 and CXCL10 genes in THP1 cells.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2023 Feb;20(2):175-188. [Abstract]

    Customer Validation
     Isoprenaline hydrochloride (ISO; 10 μM; 0, 3, 6, 9 h) inhibits the phosphorylation of MITAS366, IRF3S386 and STAT1Y701 induced by HSV-1, HSV-2 and HCMV, as well as the phosphorylation of IRF3S386 and STAT1Y701 induced by SeV, EMCV and VSV, in THP1 cells.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Food Chem Toxicol. 2023 Apr:174:113670. [Abstract]

    Customer Validation
     Isoprenaline hydrochloride (ISO; 10 μM; 6 h) pretreatment markedly restores the ATGL and HSL expressions decreased by 1,3-dichloro-2-propanol (1,3-DCP; 100 μM; 6 h) in HepG2 cells.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Death Differ. 2023 Mar;30(3):766-778. [Abstract]

    Customer Validation
     SVF differentiated adipocytes were treated with 2 μM isoprenaline (ISO) for 12h followed by Q-PCR analysis of browning genes (n=3). Gene expression is normalized to the 36B4 endogenous control.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2019 Apr 25;38(1):174.  [Abstract]

    Customer Validation
     EHD1 stabilizes β2AR. A549 cells are incubated in serum-free 1640 medium for 16 h and then treated with ISO (10 μM) for the indicated times in the presence of cycloheximide (CHX, 20 μg/mL). The cell lysates are analyzed by Western blot.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2019 Apr 25;38(1):174.  [Abstract]

    Customer Validation
     A549 cells were transfected with vector or ShEHD1 and then treated with DMSO or ISO (Isoprenaline) (10 μM; 16 h), and the EHD1 and VEGFA protein levels were assessed by immunoblotting.

  • 1/16

    Isoprenaline hydrochloride purchased from MedChemExpress. Usage Cited in: Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1373-1385. [Abstract]

    Customer Validation
     NRCMs are pre-incubated with PCA (50, 100, and 200 μM) for 1 h followed by 10 μM Isoproterenol (ISO) treatment. Cell surface area is measured by rhodamine-phalloidin staining. The expression of β-MHC is detected by Western blot.

  • Isoprenaline hydrochloride