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Cat. No.: HY-B1670

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(-)-Isoproterenol

(Synonyms: Levisoprenalinel; Proternol L)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

(-)-Isoproterenol (Levisoprenalinel) is the R-isomer of Isoproterenol. (-)-Isoproterenol can reduce the cleavage of caspase 3 and TNFα levels in retinal endothelial cells (REC). (-)-Isoproterenol can be used for the study of diabetic retinopathy.

For research use only. We do not sell to patients.

CAS No.: 51-31-0
Formula: C₁₁H₁₇NO₃
Molecular Weight:211.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

(-)-Isoproterenol Chemical Structure

CAS No.: 51-31-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Caspase 3

TNF-α

All Caspase Isoforms :

All TNF Receptor Isoforms :

In Vitro

(-)-Isoproterenol (R-1) (10 μM; 15-45 minutes) decreases both TNFα and caspase 3 levels in REC and Müller cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:

REC cells and Müller cells
Concentration:

10 μM
Incubation Time:

15, 30, and 45 minutes
Result:

Significantly decreased caspase 3 levels in REC.
Did not significantly decreased the cleaved caspase 3 levels in Müller cells.

Chemical Information

CAS No. 51-31-0
Molecular Weight 211.26
Formula C₁₁H₁₇NO₃
SMILES

OC1=CC=C([C@@H](O)CNC(C)C)C=C1O
Synonyms

Levisoprenalinel; Proternol L
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Clin Exp Hypertens

Glycyrrhetinic acid ameliorates chronic heart failure via the Nrf2 pathway. [Abstract]

2026 Dec 31;48(1):2607404. PMID: 41447318

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jayaprakash Pagadala, et al. Beta-adrenergic receptor signaling by the isomers of isoproterenol and like drugs in retinal endothelial cells and Müller cells. Med. Chem. Commun., 2011, 2, 726-730.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

(-)-Isoproterenol

1 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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(-)-Isoproterenol

Publications Citing Use of MedChemExpress (MCE) (-)-Isoproterenol

All Caspase Isoforms

All TNF Receptor Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

(-)-Isoproterenol Related Classifications

HY-B1670 Related Classifications