Identification of disease-associated gene expression signatures for mechanistic insights and drug prediction in dilated cardiomyopathy-induced heart failure

  • Mol Cell Biochem. 2026 Jan 22. doi: 10.1007/s11010-026-05486-1.
Wei Yu  #  1  2 ,  Shuai Xu  #  1  2 ,  Xin Tan  #  1  2 ,  Hangyao Zhang  1  2 ,  Ruohan Ma  1  2 ,  Yiyao Zeng  1  2 ,  Anchen Xu  1  2 ,  Honghui Tang  3 ,  Qin Rui  3 ,  Yahui Song  4 ,  Yafeng Zhou  5  6
Affiliations
  • 1. Department of Cardiology, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou, 215000, China.
  • 2. Institute for Hypertension, Soochow University, Suzhou, 215000, China.
  • 3. Center of Clinical Laboratory and Translational Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Suzhou, People's Republic of China.
  • 4. Center of Clinical Laboratory and Translational Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Suzhou, People's Republic of China. [email protected].
  • 5. Department of Cardiology, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou, 215000, China. [email protected].
  • 6. Institute for Hypertension, Soochow University, Suzhou, 215000, China. [email protected].
  • # Contributed equally.
PMID: 41569495 DOI: 10.1007/s11010-026-05486-1
Keywords
Beta-naphthoflavone; Dilated cardiomyopathy; Heart failure; Myocardial fibrosis; NOTCH signaling pathway.
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