Pelo - pelota mRNA surveillance and ribosome rescue factor Gene

Predicted to enable Endonuclease activity and metal ion binding activity. Predicted to be involved in nonfunctional rRNA decay; nuclear-transcribed mRNA catabolic process, no-go decay; and ribosome disassembly. Predicted to act upstream of or within several processes, including inner cell mass cell proliferation; mesenchymal to epithelial transition; and positive regulation of BMP signaling pathway. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human PELO (pelota mRNA surveillance and ribosome rescue factor). [provided by Alliance of Genome Resources, Apr 2022]