Lck-IN-4
Lck-IN-4 (Compound A-1) is a protein tyrosine kinase Lck inhibitor with an IC50 of 2 nM. Lck-IN-4 significantly inhibits YAP tyrosine phosphorylation and activity and induces apoptosis in cholangiocarcinoma CCA cells. Lck-IN-4 is cytotoxic in CCA tumor-derived organoids with elevated YAP activity Lck-IN-4 can be used for cancers like cholangiocarcinoma (CCA) research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1326278-38-9
- 화학식: C36H43N7O3
- 분자량:621.77
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1326278-38-9
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분자량 621.77
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화학식 C36H43N7O3
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SMILES
CC1=NC=CN2C([C@H]3CC[C@H](N4CCN(CC4)C)CC3)=NC(C5=CC(OC)=C(C=C5)NC(C6=CC7=C(OC)C=CC=C7N6C)=O)=C12
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)