LSD1-IN-21
LSD1-IN-21 (compound 5a) is a potent and BBB-penetrated LSD1 (Lysine specific demethylase-1) inhibitor, with an IC50 of 0.956 µM. LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α. LSD1-IN-21 shows good anticancer and anti-inflammatory activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C24H25N5O2S
- 분자량:447.55
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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LSD1 0.956 μM (IC50) |
LSD1-IN-21 (compound 5a) shows potent anti-cancer activity with GI50 values of 0.414 and 0.417 µM against HOP-62 and OVCAR-4 cell lines, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 447.55
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화학식 C24H25N5O2S
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SMILES
COC1=CC=C(C=C1)/C=N/NC2=C(C(C3=CC=C(C=C3)OC)=NC(SCC(C)C)=N2)C#N
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LSD1-IN-21 Related Classifications
HY-147697 Related Classifications
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