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Cat. No.: HY-182775

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PROTAC KAT6 Degrader-1

Name: PROTAC KAT6 Degrader-1
Brand: MedChemExpress
SKU: HY-182775
Price: 1600.00 USD
Availability: InStock
Rating: 5 (1 reviews)

PROTAC KAT6 Degrader-1 is a CRBN-dependented KAT6 PROTAC degrader. PROTAC KAT6 Degrader-1 inhibits cancer cells proliferation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₉H₄₆FN₉O₇S
분자량:803.90

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PROTAC KAT6 Degrader-1 Chemical Structure

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PROTAC KAT6 Degrader-1 is a CRBN-dependented KAT6 PROTAC degrader. PROTAC KAT6 Degrader-1 inhibits cancer cells proliferation^[1].

IC₅₀ & Target^[1]

Cereblon

MOZ/MORF

All PROTACs Isoforms :

All Histone Acetyltransferase Isoforms :

In Vitro

PROTAC KAT6 Degrader-1 (Compound 28) (12 nM) shows maximal fold activity ≥7.0 of ternary complex formation^[1].
PROTAC KAT6 Degrader-1 inhibits T47D cell proliferation with GI₅₀ of 10.3 nM^[1].
(Pink: target protein ligand; Blue: E3 ligase ligand; Black: linker).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 803.90
화학식 C₃₉H₄₆FN₉O₇S
SMILES

COC1=CC(N2CCN(CC2)CC(CC3)CCN3C4=CC=C(NC5C(NC(CC5)=O)=O)C=C4F)=CC=C1S(=O)(NC(C6=CC=C(C(OC)=N6)CN7C=CC=N7)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Raymond A. Ng, et al. Kat6 degrader compounds and method thereof. WO2026060321A1. 2026-03-19

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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PROTAC KAT6 Degrader-1

All PROTACs Isoforms

All Histone Acetyltransferase Isoforms