USP11-IN-1
USP11-IN-1 (Compound 26) is a selective ubiquitin-specific protease 11 (USP11) inhibitor with an IC50 of 10.9 μM. USP11-IN-1 shows IC50 values of 18.1 and >500 μM for USP4 (SI = 1.7 fold) and USP15 (SI > 100 fold). USP11-IN-1 can be used for the research of USP11-related malignant tumors.
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- 화학식: C20H25ClN4O4S
- 분자량:452.95
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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USP11 10.9 μM (IC50) |
USP4 18.1 μM (IC50) |
USP15 >500 μM (IC50) |
USP11-IN-1 exhibits potent anti-proliferative activity against PEO4 and MDA-MB-231 cells with IC50 values of 0.47 and 6.5μM, while has low cytotoxicity for MRC-5 cells (IC50 > 10 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 452.95
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화학식 C20H25ClN4O4S
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SMILES
ClC1=CC=C(CNC(C2=CC(C(CN3CCN(S(C)(=O)=O)CC3)=O)=CN2C)=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
USP11-IN-1 Related Classifications
HY-180171 Related Classifications
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