207 Results for "

fluorogenic substrate

" in MedChemExpress (MCE) Product Catalog:
Products (207)

207 Results for "fluorogenic substrate" in MCE Product Catalog:

Art. -Nr.: HY-W753820A
Synonyms: Boc-Leu-Arg-Arg-AMC TFA
Forschungsgebiete:  

Others

Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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Art. -Nr.: HY-D0146
CAS. Nr.: 87687-02-3
Synonyms: BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO - detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm .
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Art. -Nr.: HY-P0019B
CAS. Nr.: 66216-79-3
Forschungsgebiete:  

Others

Z-Gly-Gly-Arg-AMC TFA is the TFA salt form of Z-Gly-Gly-Arg-AMC (HY-P0019). Z-Gly-Gly-Arg-AMC TFA is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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Art. -Nr.: HY-P10162A
Target:  

Caspase

Forschungsgebiete:  

Others

Ac-DMQD-AMC TFA is a fluorogenic substrate for caspase-3 or caspase-10. Similar to Ac-DEVD-AMC, it releases the AMC (7-amino-4-methylcoumarin) fluorophore, resulting in fluorescence. Ac-DMQD-AMC TFA can be used to measure caspase activity in in vitro apoptosis monitoring .
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Art. -Nr.: HY-P2628
CAS. Nr.: 161877-70-9
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K + deprivation-induced apoptosis of cerebellar granule neurons .
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Art. -Nr.: HY-P4403
CAS. Nr.: 223538-61-2
Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Forschungsgebiete:  

Others

Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
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Art. -Nr.: HY-P5272
CAS. Nr.: 112844-49-2
Target:  

Bacterial

Forschungsgebiete:  

Inflammation/Immunology

Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
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Art. -Nr.: HY-P3106
CAS. Nr.: 149695-85-2
Synonyms: (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
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Art. -Nr.: HY-P2176A
Synonyms: Z-Leu-Arg-Gly-Gly-AMC TFA
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Z-LRGG-AMC TFA is the trifluoroacetate salt of Z-LRGG-AMC (HY-P2176). Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon cleavage of Z-LRGG-AMC TFA by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify isopeptidase T activity (Ex/Em : 360/460 nm) .
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Art. -Nr.: HY-138658
Synonyms: JF526, SE; JF526, NHS
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 526/550 nm).
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Art. -Nr.: HY-169491
CAS. Nr.: 1224691-12-6
Target:  

Fluorescent Dye

Forschungsgebiete:  

Metabolic Disease

Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively .
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Art. -Nr.: HY-W776853
CAS. Nr.: 53643-14-4
4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside is a fluorogenic substrate with activity for lysozyme assays. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside can be used to study enzyme activity and its applications in biomedicine. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside exhibits high sensitivity in analyzing enzyme reactions in biological samples.
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Art. -Nr.: HY-P3098
CAS. Nr.: 256394-94-2
Target:  

MMP

Forschungsgebiete:  

Others

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .
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Art. -Nr.: HY-P3120
CAS. Nr.: 1926163-82-7
Target:  

MMP Fluorescent Dye

Forschungsgebiete:  

Others

Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2, upon cleavage by MMP-14, releases 7-methoxycoumarin-4-acetyl (Mca) (Ex/Em = 328/420 nm).
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Art. -Nr.: HY-P3120A
CAS. Nr.: 2237216-67-8
Target:  

MMP Fluorescent Dye

Forschungsgebiete:  

Others

Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 TFA is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 TFA, upon cleavage by MMP-14, releases 7-methoxycoumarin-4-acetyl (Mca) (Ex/Em = 328/420 nm).
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Art. -Nr.: HY-P3364A
Forschungsgebiete:  

Others

Ac-QPKK(Ac)-AMC acetate is a p53-derived peptide conjugated with a fluorophore, which serves as a fluorescent peptide substrate for detecting the deacylase activity of zinc-dependent HDACs and sirtuins (Ex = 360 nm; Em = 460 nm) .
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Art. -Nr.: HY-P11367
CAS. Nr.: 118850-78-5
Forschungsgebiete:  

Infection Metabolic Disease

Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .
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Art. -Nr.: HY-123000
CAS. Nr.: 124223-99-0
Reinheit:  ≥99.0%
4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.
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Art. -Nr.: HY-142021
CAS. Nr.: 156192-32-4
Reinheit:  99.24%
Target:  

Cathepsin Parasite

Forschungsgebiete:  

Infection Inflammation/Immunology

Z-Leu-Arg-AMC is a fluorogenic peptide substrate for cysteine proteases (e.g., Cathepsin) (Ex=350 nm,Em=460 nm). Z-Leu-Arg-AMC is preferentially cleaved by Cathepsin K and S under weakly acidic conditions, while its hydrolysis relies on residual Cathepsin S activity at neutral pH. Z-Leu-Arg-AMC serves as a substrate for recombinant Sphenophorus levis Cathepsin L, falcipain-2, falcipain-3, berghepain-2, knowlepain-2, vivapain-2, as well as falcipain-2 chimeras and constructs. It enables quantitative detection of cysteine protease activity in human inflammatory bronchoalveolar lavage fluid via fluorescence generation. Z-Leu-Arg-AMC can be used in research related to pulmonary inflammatory diseases and malaria .
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Art. -Nr.: HY-131026
Synonyms: JF635, SE; JF635, NHS
Janelia Fluor 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 635/652 nm).
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