![[Ala28]-β Amyloid(25-35) TFA](https://file.medchemexpress.com/product_pic/hy-p5968a.gif "Click to View [Ala28]-β Amyloid(25-35) TFA Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
β-amyloid aggregation
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "β-amyloid aggregation" in MCE Product Catalog:
10
Target:
Research Areas:
Carbenoxolone is a blood-brain barrier-permeable Pannexin1 inhibitor, gap junction (Gap junction) blocker, and β-amyloid 42 inhibitor. Carbenoxolone modulates voltage-gated currents of wild-type and mutant Panx1, and inhibits stimulus-activated Panx1 channel function. Carbenoxolone interacts with stable residues of β-amyloid 42 peptides, fibrils and oligomers, thereby inhibiting their aggregation. Carbenoxolone alleviates liver fibrosis. Carbenoxolone exerts neuroprotective and nootropic effects. Carbenoxolone can be used in studies related to Alzheimer's disease and liver fibrosis .
1
Target:
Research Areas:
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound . ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease .
Cat. No.: HY-W012898
CAS No.: 95-45-4
Synonyms: Biacetyl dioxime
Target:
Research Areas:
Dimethylglyoxime (Biacetyl dioxime) is an oxime compound. Dimethylglyoxime selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime is used in the research of Alzheimer's disease .
Cat. No.: HY-W117986
CAS No.: 352525-91-8
Research Areas:
Aβ aggregation-IN-1 (Compound 1b) is a β-amyloid aggregation inhibitor/depolymerizer, with IC50 values of 3.92 μM and 7.19 μM, respectively. Aβ aggregation-IN-1 inhibits the activation of preformed β-amyloid fibrils, reactive oxygen species (ROS) and Caspase-3. Aβ aggregation-IN-1 can be used in research related to Alzheimer's disease .
Cat. No.: HY-P1378A
Target:
Research Areas:
Cat. No.: HY-W004287
CAS No.: 1731-88-0
Category:
Target:
Cat. No.: HY-P1378
CAS No.: 134500-80-4
Target:
Research Areas:
Cat. No.: HY-148495
Purity: ≥90.0%
Target:
Research Areas:
Carnosine conjugated hyalyronate is a hyaluronic acid derivative functionalized with the dipeptide carnosine (Carnosine, Car) and has the ability to resist Aβ amyloid aggregation. Carnosine conjugated hyalyronate dissolves amyloid fibrils and reduces Aβ-induced toxicity in vitro. The effectiveness of Carnosine conjugated hyalyronate against amyloid aggregation is directly proportional to the Carnosine loading .
Cat. No.: HY-P1051
CAS No.: 107015-83-8
Synonyms: amyloid β-Protein (12-28)
Target:
Research Areas:
Cat. No.: HY-P1388F
Synonyms: FITC-Ahx-amyloid β-peptide (1-42) (rat/mouse) tris
Target:
Research Areas:
Cat. No.: HY-B1588S
Cat. No.: HY-146142
CAS No.: 1946008-31-6
Target:
Research Areas:
AChE/BuChE-IN-2 (Compound 5f) is an orally active AChE and BuChE inhibitor with IC50 values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows a non-competitive inhibition with AChE and shows potent self-induced β-amyloid (Aβ) aggregation inhibition with an IC50 of 62.52 μM. AChE/BuChE-IN-2 can cross the BBB .
Cat. No.: HY-P5968A
Synonyms: β(25-35)KA TFA
Target:
Research Areas:
Cat. No.: HY-P1051A
Synonyms: amyloid β-Protein (12-28) TFA; amyloid Beta-Peptide (12-28) (human) TFA; β-amyloid protein fragment(12-28) TFA
Target:
Research Areas:
Cat. No.: HY-P10037
CAS No.: 131580-11-5
Target:
Research Areas:
Cat. No.: HY-W004287S
CAS No.: 1219804-90-6
Cat. No.: HY-W004287R
CAS No.: 1731-88-0
Category:
Cat. No.: HY-157441
Target:
Research Areas:
AChE/Aβ-IN-4 is a dual inhibitor of acetylcholinesterase (AChE) and β-amyloid (Aβ) aggregation, with the IC50 values of 1.72 ± 0.18 μM and 1.42 ± 0.3 μM, respectively. AChE/Aβ-IN-4 plays an impotant role in neurological disorders, such as Alzheimer’s disease .
Cat. No.: HY-W540926
CAS No.: 75006-64-3
Synonyms: Biacetyl dioxime sodium hydrate
Target:
Research Areas:
Dimethylglyoxime sodium hydrate (Biacetyl dioxime sodium hydrate) is an oxime compound. Dimethylglyoxime sodium hydrate selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime sodium hydrate inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime sodium hydrate is used in the research of Alzheimer's disease .
Cat. No.: HY-P5370
CAS No.: 1678415-68-3
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
