352525-91-8
Chemical Structure
Aβ aggregation-IN-1
- CAS No.: 352525-91-8
- Formula:C9H8BF3O2
- Molecular Weight:215.97
IUPAC Name: (E)-(4-(trifluoromethyl)styryl)boronic acid
InChIKey: BBNQFBHQOPZKTI-AATRIKPKSA-N
SMILES: FC(F)(F)C1=CC=C(/C=C/B(O)O)C=C1
Biological Activity: Aβ aggregation-IN-1 (Compound 1b) is a β-amyloid aggregation inhibitor/depolymerizer, with IC50 values of 3.92 μM and 7.19 μM, respectively. Aβ aggregation-IN-1 inhibits the activation of preformed β-amyloid fibrils, reactive oxygen species (ROS) and Caspase-3. Aβ aggregation-IN-1 can be used in research related to Alzheimer's disease[1].
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Aβ aggregation-IN-1 | 99.92% | Aβ aggregation-IN-1 (Compound 1b) is a β-amyloid aggregation inhibitor/depolymerizer, with IC50 values of 3.92 μM and 7.19 μM, respectively. Aβ aggregation-IN-1 inhibits the activation of preformed β-amyloid fibrils, reactive oxygen species (ROS) and Caspase-3. Aβ aggregation-IN-1 can be used in research related to Alzheimer's disease. | ||||||||||||||||||||
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Keywords